A passenger train has derailed in Philadelphia, killing at least five people and injuring dozens of others, officials in the US city say.
Up to 10 carriages of the Washington-New York Amtrak service went off the track on Tuesday evening.
Emergency officials and fire-fighters are at the scene looking for passengers who may be trapped in the wreckage.
More than 240 people were on board Train 188, the officials say. It is not known what caused the derailment.
The National Transportation Safety Board said it was dispatching a team of investigators to the crash site.
'Mangled up'
The train derailed in a suburb of Philadelphia, shortly after leaving the city's main station.
Philadelphia Mayor Michael Nutter said at least five people died.
"It is a devastating scene," he told reporters. "Never seen anything like this in my life."
"We walked the entire length of the train area. The engine [is] completely separated from the rest of the train and one of the cars is perpendicular to the rest of the cars. It's unbelievable."
Mr Nutter also said that according to preliminary information 243 people were on the train.
A fire official was quoted as saying that more than 50 people were taken to hospital, six of them critically injured.
